Healthcare professional at the patient bedside in front of the PrisMax System

CRRT Filtersets

Vantive CRRT filtersets maximize simplicity and efficiency

Each CRRT filterset can be used with all CRRT modalities and with any anticoagulant protocol, so there is no need to list multiple types on the order set or to keep several types in inventory. CRRT modalities can be changed during therapy without changing the set.

Compatible Products

Acute Therapy Systems
CRRT Solutions
Organ Support Filtersets
Digital Solutions

CRRT filterset features

Suitable for all CRRT prescriptions

Each CRRT filterset works with all CRRT modalities and any anticoagulant protocol, providing flexibility to meet patient needs and create operational efficiencies.

Unique clearance mechanism

Vantive’s AN69ST membrane has a unique mechanism of action that adsorbs1 the higher-molecular-weight toxins that can be present in patients with AKI.

Exclusively for PrisMax and Prismaflex systems

Engineered to work with the PrisMax and Prismaflex systems, Vantive’s CRRT filtersets are bar-coded for set recognition, with step-by-step setup guidance supporting reduced downtime and lasting therapy proficiency.2

See how Vantive filtersets maximize simplicity and efficiency.

Simplify therapy set-up and management

Vantive CRRT filters are permanently pre-connected to color-coded tubing lines for easy setup and accurate connection between lines and bags.3 Each set is a closed system, minimizing setup steps and reducing the potential for touch contamination.3
 
The pre-connected filtersets have a specifically designed deaeration chamber to help remove air without user intervention, eliminate the blood and air interface, and reduce blood clot formation.2

Optimize operational efficiencies in the ICU

Vantive CRRT filtersets help reduce inventory requirements and optimize operational efficiencies because each set can work with all CRRT modalities and any anticoagulant protocol, as noted in the table below.4 Each filterset is bar-coded for set recognition on the PrisMax and Prismaflex systems, with setup guidance to support reduced therapy downtime and offer lasting therapy proficiency.2

A healthcare professional at the patient's bedside working with the PrisMax system

Meet clinical needs across CRRT modalities

 

Membrane

Minimal patient size

SCUF

CVVH

CVVHD

CVVHDF

Heparin

No anti-coagulant

ST60

AN69ST

11 kg

  ✓  ✓  ✓   ✓   ✓    ✓

ST100

AN69ST

30 kg

  ✓  ✓  ✓   ✓   ✓   ✓

ST150

AN69ST

30 kg

  ✓  ✓ ✓   ✓   ✓   ✓

Membrane options to fit individual patient needs

Vantive’s CRRT filtersets include options for adult patients and for low-body-weight patients, all with lower extracorporeal blood volumes. 

Vantive CRRT filtersets feature the unique AN69ST membrane for exceptional biocompatibility and a unique adsorptive capability to clear the higher-molecular-weight toxins that may be present in patients with AKI.1

AN69ST membrane for AKI attracts large molecules

Since patients with AKI can have higher-molecular-weight toxins present in their blood, the AN69ST membrane has a unique mechanism of action that adsorbs1 higher molecular weight toxins such as myoglobin, and beta 2 microglobulin, in addition to the smaller uremic toxins removed by industry-standard polysulfone-based filter membranes.

The distribution of sulfonate groups throughout the membrane structure allows adsorption to occur on the surface and across the whole membrane, which results in stable membrane performance over time.1

AN69_membrane_vs_PAES_membrane

See how the unique adsorption function of the AN69ST filterset removes higher-molecular-weight toxins that may be present in AKI.

A variety of AN69ST filtersets to meet prescription targets

The AN69ST membrane is available in three different sizes to help meet individual patient needs.

 ST60 setST100 setST150 set
Membrane effective surface area0.6 m21 m21.5 m2
Blood volume in set97 mL155 mL193 mL
Minimal patient weight11 kg30 kg30 kg

Related products

Important Safety Information

INTENDED USE

The Prismaflex and PrisMax Systems are intended for:

  • Continuous Renal Replacement Therapy (CRRT) for patients weighing 20 kilograms or more with acute renal failure and/or fluid overload.
  • Therapeutic Plasma Exchange (TPE) therapy for patients weighing 20 kilograms or more with diseases where fluid removal of plasma components is indicated.

INTENDED USE

The Prismaflex ST set is a single-use device that provides blood purification through a semipermeable membrane. The Prismaflex ST set is for use only in conjunction with the Prismaflex control unit or with the PrisMax control unit (in countries where PrisMax is cleared or registered). All treatments administered via the Prismaflex ST sets must be prescribed by a physician. The size, weight, state of uremia, cardiac status, and general physical condition of the patient must be carefully evaluated by the prescribing physician before each treatment.

If patients suffer from acute kidney injury and / or volume overload, the Prismaflex ST set is indicated for continuous renal replacement therapies (CRRT), in modalities such as:

  • Slow Continuous UltraFiltration (SCUF)
  • Continuous Veno-Venous Hemofiltration (CVVH)
  • Continuous Veno-Venous HemoDialysis (CVVHD)
  • Continuous Veno-Venous HemoDiaFiltration (CVVHDF) to perform fluid management and reduction of uremic toxins.

The Prismaflex ST100 set and ST150 are indicated for use in patients with a body weight equal or greater than 30kg (66lb) and Prismaflex ST60 set is indicated to patients with a body weight greater than 11kg (24lb).

Rx Only. For safe and proper use of the products mentioned herein, please refer to the appropriate Operator’s Manual or Instructions for Use.

 

Vantive, AN69, Prismaflex and PrisMax and are trademarks of Vantive Health LLC or its affiliates.

References

  1. Thomas M, Moriyama K, Ledebo I. AN69ST: Evolution of the world's first high permeability membrane. Contrib Nephrol. 2011;173:119-129.

  2. Vantive Health LLC. PrisMax Operator’s Manual. AW8061. May, 2022.

  3. Vantive Health LLC. ST60/ST100/ST150 sets with AN69 Spec Sheet. 1000015673. August, 2024. Internal Documentation.

  4. Vantive Health LLC. FMC Product Range Acute Therapies, 2014. Internal Documentation.